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Ismo (Isosorbide-5-Mononitrate) is a medication used for preventing angina (chest pain) symptoms which appear because of heart disease.

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About Ismo

Ismo is medicine that prevents Angina, which can be result of heart disease.

Ismo should be used as directed by doctor.

  • It is not recommended to stop taking Ismo suddenly. There is a risk of side effects like angina attacks. If there is a need to stop taking the medicine, or add a new one, ask your doctor to gradually lower the dose.
  • Ismo should be taken orally, no matter with or without food.
  • Take the medicine twice a day, with the doses 7 hours apart. It is better to take the first dose in the morning right after waking up, if your doctor didn’t directed otherwise.

Ismo refers to class of nitrate vasodilators, which work by widening the blood vessels, that in its turn reduces the pressure on heart and helps to prevent and decrease chest pain.

If you miss a dose of Ismo, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

It is recommended to keep Ismo at room temperature (at about 60 - 85 degrees F (15 and 30 degrees C) and far from heat, moisture and sunlight. Do not store in the kitchen and in the bathroom because Ismo mustn’t be affected by moisture and heat. Keep Ismo out of the reach of children and away from pets.

Ismo Safety information

Do not use Ismo in such cases:

  • you have ever had allergic reaction to any ingredient in Ismo or to other nitrate medicines;
  • recently you took Sildenafil(Viagra) or Tadalafil(Cialis);
  • you drink a lot of alcohol daily.


  • Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Ismo may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Do not drink alcohol while you are taking Ismo.
  • When you begin taking Ismo, headaches are likely to occur. Ask your doctor for instructions on ways to reduce this side effect.
  • Ismo should not be used to stop an attack of angina; it is intended only for prevention of an attack.
  • Isosorbide-5-Mononitrate may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Ismo.
  • Ismo should not be used in children; safety and effectiveness in children have not been confirmed.
  • If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ismo while you are pregnant. It is not known if Ismo is found in breast milk. If you are or will be breast-feeding while you use Ismo, check with your doctor. Discuss any possible risks to your baby.

Ismo is to be used only by the patient for whom it is prescribed. Do not share it with other people.

Ismo Side effects

Ismo may cause some side effects as a majority of medications, but many people have no side effects from Isosorbide-5-Mononitrate. Inform your doctor if these possible side effects persist or become bothersome:

  • Dizziness;
  • Headache.

Call emergency if you suddenly experienced:

  • severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue);
  • changes in vision; fainting;
  • numbness of an arm or leg; severe stomach pain
  • other side effects not listed in this guide (they are also possible, but very unlikely).

If your symptoms do not improve or if they become worse, consult with your doctor for further instructions concerning your treatment.

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