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Prometrium (Progesterone) is a medicine to treat women problems associated with progesterone levels such as lack of periods or other conditions. Lower the risk of cancer.

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About Prometrium

Progesterone is a female hormone used to protect the lining of the uterus in women on estrogen replacement therapy, to treat women who have had menstrual periods in the past but have stopped having them because of a lack of Progesterone hormone and to treat other conditions as determined by your doctor. Progesterone may lower the risk of estrogen-related cancer of the uterus.

Follow the directions for using this medicine provided by your doctor. Read a patient information leaflet, which comes with this medicine, carefully. Ask your doctor, nurse, or pharmacist any questions you may have about this medicine.

Prometrium is a form of natural Progesterone and the only type that can be taken by mouth. It is only available by prescription.

If you miss a dose of Prometrium, do not take 2 doses at once, skip the missed dose and go back to your regular dosing schedule.

Store Progesterone at room temperature at 77 degrees F (25 degrees C) in a tightly-closed container, away from heat, moisture, and light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted.

Prometrium Safety information

If you have had an allergic reactions Progesterone or to any ingredient in this product, such as peanut oil, do not take it. You may check your progress or side effects by laboratory and/or medical tests, including blood pressure, breast and pelvic examinations, PAP tests (for endometrial cancer), mammogram, and other tests. Follow your doctor's instructions to perform monthly breast self-examinations and report any lumps immediately. Keep all doctor and laboratory appointments while you are taking Prometrium. If you take this medicine for an extended period of time, you should be evaluated regularly by your doctor to determine if you need to continue taking this medicine. This medicine may affect certain lab test results. Make sure all of your doctors and laboratory personnel know that you are taking this medicine. Before you have any medical or dental treatments, emergency care, surgery or be confined to a bed or chair for a long period of time (such as a long plane flight) tell the doctor or dentist that you are using this medicine beforehand. Special precautions may be needed in these circumstances while you are taking this medicine. Using this medicine alone, with other medicines, or with alcohol may cause drowsiness or dizziness or lessen your ability to drive or to perform other potentially dangerous tasks. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Prometrium. Caution is advised when using this medicine in the elderly because they may be more sensitive to the effects of this medicine, especially the risk of dementia. For women: if you are pregnant or if you suspect that you could be pregnant, do not use this medicine and contact your doctor immediately. This medicine is excreted in breast milk. If you are or will be breast-feeding while you are using this medicine, check with your doctor or pharmacist to discuss the risks to your baby. This medicine should not be used in combination with estrogen to prevent the risk of heart disease (including heart attacks), stroke, serious blood clots in the lung (pulmonary embolism) or leg (deep venous thrombosis), cancer of the breast, dementia, or cancer of the ovary. It depends on the length of time this combination of medicines is used and the amount of estrogen per dose. Therefore, the combination of estrogen and this medicine should be used for the shortest possible length of time at the lowest effective dose. Consult your doctor/pharmacist for details. Do not start or stop any medicine before doctor or pharmacist approves it. Inform your doctor of any other medical conditions including heart problems, circulation problems, high blood pressure, family history of blood clots, womb problems (such as endometriosis), asthma, migraine headaches, any current or previous cancers, bleeding problems, liver problems, kidney problems, history of depression, diabetes, seizure disorders, history of tobacco use, cholesterol or lipid problems, lupus, thyroid problems, high calcium levels in your blood, if you have had a recent miscarriage, any allergies, pregnancy, or breast-feeding. If you have a history of blood clots or clotting problems; cancer of the breast, ovary, or uterus; severe liver problems; undiagnosed vaginal bleeding; recent (within the past year) heart attack; or history of stroke it is not recommended to use this medicine.

Do not share this medicine with others for whom it was not prescribed. Do not use this medicine for other health conditions. If using this medicine for an extended period of time, obtain refills before your supply runs out. Keep this medicine out of the reach of children.

Prometrium Side effects

Side effects that may occur while taking this medicine include sleepiness or tiredness, dizziness, cough, nausea, vomiting, cramps, bloating, worry, irritability, diarrhea, constipation, headache, breast tenderness, stomach upset, acne, or dry mouth.

Notify your nurse quickly in case they continue or are bothersome, if you experience pain or cramping in the muscles or joints; difficulty urinating or change in the amount of urine produced; swelling of hands or feet; unexplained weight changes; fainting; vaginal discharge; or breast pain, if you experience fever or chills; swelling, or tenderness; unusually fast heartbeat; sharp or crushing chest pain; darkening of urine; sudden shortness of breath; sudden leg pain; sudden severe headache, vomiting, dizziness, or fainting; numbness of an arm or a leg; slurred speech; severe stomach pain; mental or mood changes (such as severe depression, memory loss, or confusion); coughing up blood; yellowing of eyes/skin; vision problems or changes (including sudden, partial, or full loss of vision); stomach swelling, pain, maybe tenderness; abnormal vaginal bleeding; lump in the breast; or seizure.

An allergic reaction to Progesterone does not happen often, but seeks immediate medical attention if it occurs. If you suddenly felt the symptoms of an allergic reaction, expressed in rash, itching, swelling, trouble breathing, severe dizziness, or other effects not listed above, contact your doctor, nurse, or pharmacist.

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