News
19August2009
Researches have found that a drug used to treat Type 2 diabetes - pioglitazone and rosiglitazone lead to the increased risk of heart failure and death among elder patients.
Its known, that these drugs are useful in controlling blood sugar levels.
However, both drugs can also cause side effects including weight gain, fluid retention and heart failure.
The doctors didnt know for certain any clinically significant differences in the cardiac safety of pioglitazone and rosiglitazone.
That is why study, made in Canada compared the risk of heart attack, heart failure and death in patients treated with these two drugs. They identified about 40,000 patients aged 66 years and older, with the help of prescription records.
This examination has shown that patients treated with pioglitazone had a considerably lower risk of heart failure and death compared to patients treated with rosiglitazone. But, there was no important difference in the risk of heart attack.
Researches suppose, that for every 93 patients treated with rosiglitazone instead of pioglitazone, one extra cardiovascular event or death would be predicted to occur yearly.
Diabetic drugs cause heart failure
Researches have found that a drug used to treat Type 2 diabetes - pioglitazone and rosiglitazone lead to the increased risk of heart failure and death among elder patients.Its known, that these drugs are useful in controlling blood sugar levels.
However, both drugs can also cause side effects including weight gain, fluid retention and heart failure.
The doctors didnt know for certain any clinically significant differences in the cardiac safety of pioglitazone and rosiglitazone.
That is why study, made in Canada compared the risk of heart attack, heart failure and death in patients treated with these two drugs. They identified about 40,000 patients aged 66 years and older, with the help of prescription records.
This examination has shown that patients treated with pioglitazone had a considerably lower risk of heart failure and death compared to patients treated with rosiglitazone. But, there was no important difference in the risk of heart attack.
Researches suppose, that for every 93 patients treated with rosiglitazone instead of pioglitazone, one extra cardiovascular event or death would be predicted to occur yearly.
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