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Montelukast is used for treating such diseases as asthma and seasonal allergic rhinitis. The first sign of the effect can be indicated after using Montelukast for the period of 3 to 14 days and cannot be used for the treatment of acute asthma attacks. Singulair was approved by the FDA in 1998.

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About Singulair

Take Montelukast by mouth. This edicine is leukotriene receptor antagonist. It is widely used for treatment of asthma and relieving seasonal allergic rhinitis. Montelukast is a very safe medicine. It is approved by FDA and can be used for children from 6 months of age. It works in a way that is similar to zafirlukast (Accolate), which includes blocking the binding of some leukotrienes, but unlike zafirlukast, Singulair does not inhibit the sbstantial enzymes in the liver. Thus, unlike zafirlukast, Montelukast is not considered to affect the exclusion of other drugs.

Leukotrienes are naturally occurring chemicals in the organism that stimulate excitation of asthma and seasonal allergic rhinitis and of other diseases in which excitation is significant (for example allergy). They are bodied by cells, released, and then bound to other cells, and it is the process of binding to these other cells that is a stimulus for the cells to develop further inflammation.

The recommended dose of the product is 4, 5, or 10 mg every day. The dose for children is 4 and 5 mg tablets. You should take Montelukast in the evening with or without food.

In case of missing a dose, you should take the missed dose as soon as you remember to. But, if the time has almost come to take the next one, you should skip the missed dose and return to your directed schedule of using the product. You should not take a double dose of the medicine.

Store Singulair at room temperature of 15-30 degrees C (59-86 degrees F). Do not expose to moisture and light.

Singulair Safety information


  • You should avoid items or actions that can provoke further asthma attacks.
  • The blood concentration of Montelucast is increased by 40% when using Phenobarbital, so to speak about Rifampin. Therefore, when you are prescribed these drugs the doses of Montelukast may need to be reduced.
  • Do not use Singulair during pregnancy and do not breast-feed during treatment with Singulair.

Singulair Side effects

The most general side-effects that can be impacted by Montelukast include headache, dizziness, abdominal pain, sore throat, and rhinitis (inflammation of the inner lining of the nose). The frequency of side effects is exhibited in 1 in 50 to 1 in 7 persons who take Montelukast.

In case you have any serious side-effects such as severe allergic reaction, a rash or unexplained open sores or bruising; a flu-like illness or severe inflammation (pain and swelling) of the sinuses stop using Montelukast immediately and consult your doctor at once to seek emergency medical attention.

The side-effects not included in the lists may also occur. If so, talk to your doctor about any side-effect that bothers you or seems either suspicious or strange to you.

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